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The discovery of a potential link between Inflammatory Bowel Disease (IBD) and mental health symptoms suggests a possible brain-gut connection. The study titled “Associations between brain morphology, inflammatory markers, and symptoms of fatigue, depression, or anxiety in active and remitted Crohn’s disease (CD)” reveals compelling evidence of brain-gut dysfunction.

Patients with active disease tend to experience symptoms of fatigue and compromised mental health, along with reduced gray matter volume in specific cortical and subcortical regions.

This research paves the way for further exploration of therapeutic interventions targeting brain-gut interactions to alleviate symptom burden and improve patient outcomes.

Find more information about the research in the Journal of Crohn’s and Colitis.